
James Renwick Jr. designed some of the most important buildings of nineteenth-century New York and Washington, including Grace Church, the Smithsonian Institution Building, St. Patrick's Cathedral, and the Corcoran Gallery.
The Smallpox Hospital was one of his earliest major commissions. He was just 35 when he began designing it.
In 1853, Archbishop John Hughes engaged Renwick to design St. Patrick's Cathedral on Fifth Avenue. The following year, Renwick began designing the Smallpox Hospital on Blackwell's Island.

Fifth Avenue, New York

Blackwell's Island, New York
Southern end · 1854–1856
Designed as a hospital for the treatment and isolation of people with smallpox.
Northern end · 1872
Designed as a lighthouse marking the East River channel.
At the northern end, the Blackwell Island Lighthouse still marks the East River channel. At the southern end, the Smallpox Hospital remains as a ruin.
